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Shahidian, Azadeh, Tahouneh, Sanam. (1403). A comprehensive overview of micromixers and micropumps in biomechanical applications. فناوری آموزش, (), -. doi: 10.22061/jcarme.2025.10035.2349
Azadeh Shahidian; Sanam Tahouneh. "A comprehensive overview of micromixers and micropumps in biomechanical applications". فناوری آموزش, , , 1403, -. doi: 10.22061/jcarme.2025.10035.2349
Shahidian, Azadeh, Tahouneh, Sanam. (1403). 'A comprehensive overview of micromixers and micropumps in biomechanical applications', فناوری آموزش, (), pp. -. doi: 10.22061/jcarme.2025.10035.2349
Shahidian, Azadeh, Tahouneh, Sanam. A comprehensive overview of micromixers and micropumps in biomechanical applications. فناوری آموزش, 1403; (): -. doi: 10.22061/jcarme.2025.10035.2349

A comprehensive overview of micromixers and micropumps in biomechanical applications

Journal of Computational & Applied Research in Mechanical Engineering (JCARME)
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 28 بهمن 1403    اصل مقاله (1.23 M)
نوع مقاله: Review paper
شناسه دیجیتال (DOI): 10.22061/jcarme.2025.10035.2349
نویسندگان
Azadeh Shahidian* ؛ Sanam Tahouneh
Department of mechanical engineering, K. N. Toosi university of technology, 19919-43344, Tehran, Iran
تاریخ دریافت: 09 مرداد 1402،  تاریخ بازنگری: 22 بهمن 1403،  تاریخ پذیرش: 28 بهمن 1403 
چکیده
In recent years, microfluidic devices have had various applications, such as the biological field. Hence, it is essential to study fluid flow governing equations in order to realization and ability to better control fluids in different flow regimes according to microfluidic devices. Also, study of inducing source, fabrication technique, and numerical procedure of fluid flow simulation are necessary for flow solution and are used to select proper devices.
Here, the mentioned cases have been studied. As well, numerical methods of fluid flow study for various type of fluid, their comparison and pros and cons of each of them have been briefly expressed that may be used for the development of them. Then, the extensive biological application of micromixers and micropumps have been investigated. It is expected that this paper will be of attention to scholars or practitioners in the micromixer and micropump biomedical technology field and those who enter this context for the first time and may also highlight what will assist in future development.
کلیدواژه‌ها
Micromixer؛ Micropump؛ Fabrication method؛ Numerical procedure؛ Biological application
مراجع
[1] N.T. Nguyen, S.T. Wereley, A. Mousavi Shaegh, Fundamentals and Applications of Microfluidics, Third Edition (2019).

[2] B. J. Kirby, Micro and nanoscale fluid mechanic, transport in microfluidic devices, Cambridge University Press, (2010).

[3] Y. Li, W.V. Roy, P.M. Vereecken, L. Lagae, "Effects of laminar flow within a versatile microfluidic chip for in-situ electrode characterization and fuel cells", Microelectron. Eng.,Vol. 181, pp. 47-54, (2017).

[4] R.J. Yang, H.H. Hou, Y.N. Wang, L.M. Fu, "Micro-magnetofluidics in microfluidic systems: A review", Sens. Actuators B: Chem.,Vol. 224, pp. 1-15, (2016).

[5] J.W. Thies, P. Kuhn, B. Thürmann, S. Dübel, A. Dietzel, "Microfluidic quartz-crystal-microbalance (QCM) sensors with specialized immunoassays for extended measurement range and improved reusability", Microelectron. Eng., Vol. 79, pp. 25-30, (2017).

[6]  H.T. Nguyen, L.S. Bernier, A.M. Jean, R. Trouillon, M.A.M. Gijs, "Microfluidic-assisted chromogenic in situ hybridization (MA-CISH) for fast and accurate breast cancer diagnosis", Microelectron. Eng., Vol. 183-184, pp. 52-57, (2017).

[7] R.J. Yang, C.C. Liu, Y.N. Wang, H.H. Hou, L.M. Fu, "A comprehensive review of micro-distillation methods", Chem. Eng. J., Vol. 313, pp. 1509-1520, (2017).

[8] T.L. Chang, C.H. Huang, S.Y. Chou, S.F. Tseng, Y.W. Lee, "Direct fabrication of nanofiber scaffolds in pillar-based microfluidic device by using electrospinning and picosecond laser pulses", Microelectron. Eng., Vol. 177, pp. 52-58, (2017).

[9] F. Yi-Qiang, W. Hong-Liang, G. Ke-Xin, Liu Jing-Ji, C. Dong-Ping, Z. Ya-Jun, "Applications of Modular Microfluidics Technology", Chines J. Anal. Chem., Vol. 46, No. 12 (2018).

[10] R.J. Yang, H.H. Hou, Y.N. Wang, L.M. Fu, "Micro-magnetofluidics in microfluidic systems: a review", Sens. Actuators B: Chem., Vol. 224, pp. 1–15, (2016).

[11]https://www.elveflow.com/microfluidic-reviews/general-microfluidics/a-general-overview-of-microfluidics/

[12] P. Tabeling, Introduction to Microfluidics, Oxford university press (2015).

[13] Ch.Y. Lee,  L.M. Fu,  "Recent advances and applications of micromixers", Sens. Actuators B, Vol. 259, pp.  677–702, (2018).

[14] Y.N. Wang, L.M. Fu, "Micropumps and biomedical applications – A review", Microelectron. Eng., Vol. 195, pp. 121-138 (2018).

[15] A. Cobo, R. Sheybani, H. Tu, E. Meng, "A Wireless Implantable Micropump for Chronic Drug Infusion Against Cancer", Sens. Actuators A: Phys., Vol. 239, pp. 18-25  (2016).

[16] T.T. Nguyen, N.S. Goo, V.K. Nguyen, Y. Yoo, S.Z Park, "Design, fabrication, and experimental characterization of a flap valve IPMC micropump with a flexibly supported diaphragm", Sens. Actuators A, Vol. 141, No. 2, pp. 640–648,  (2008).

[17]  L. Jiang, Y. Zeng, Q. Sun, Y. Sun, Z. Guo, J.Y. Qu, S. Yao, "Microsecond protein folding events revealed by time-resolved fluorescence resonance energy transfer in a microfluidic mixer", Anal. Chem., Vol. 87, No. 11, pp.  5589–5595, (2015).

[18] Y. Gambin, V. VanDelinder, A.C.M. Ferreon, E.A. Lemke, A. Groisman, A.A. Deniz, "Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing", Nat. Methods,Vol. 8, No. 3, pp. 239-241, (2011).

[19] Ch. Liu, Y. Li, B.F. Liu, "Micromixers and their applications in kinetic analysis of biochemical reactions", Talanta, Vol. 205,  120136, (2019).

[20]  A. Plumridge, A.M. Katz, G.D. Calvey, L. Pollack, R. Elber, S. Kirmizialtin, "Revealing the distinct folding phases of an RNA three-helix junction", Nucleic Acids Res., Vol. 46, No.  14, pp. 7354–7365, (2018).

[21] A.J. deMello, "Control and detection of chemical reactions in microfluidic systems", Nature, Vol. 442, No. 7101 ,pp. 394–402, (2006).

[22]  L. Capretto, W. Cheng, M. Hill, X.L. Zhang, Micromixing within microfluidic devices, Microfluidics: Technologies and Applications, pp. 27–68, (2011).

[23]  L.M. Fu, R.J. Yang, C.H. Lin, Y.S. Chien, "A novel microfluidic mixer utilizing electrokinetic driving forces under low switching frequency", Electrophoresis, Vol.26, No. 9, pp.1814–1824 ,(2005).

[24] S. Kim, A.M. Streets, R.R. Lin, S.R. Quake, S. Weiss, D.S. Majumdar, "Highthroughput single-molecule optofluidic analysis", Nat. Methods, Vol. 8, No. 3, pp. 242–245, (2011).

[25]  C.Y. Chen, C.Y. Lin, Y.T. Hu, Magnetically actuated artificial cilia for optimum mixing performance in microfluidics, Lab Chip, Vol. 13, No. 14, pp. 2834–2839, (2013).

[26] ] V. Hessel, H. Lowe, F. Schonfeld, "Micromixers—a review on passive and active mixing principles", Chem. Eng. Sci., Vol. 60, No. 8, pp. 2479–2501, (2005).

[27] Z.G. Wu, N.T. Nguyen, "Convective-diffusive transport in parallel lamination micromixers", Microfluid. Nanofluidics, Vol. 1, No. 3, pp. 208–217, (2005).

[28] D.E. Hertzog, X. Michalet, M. Jager, X.X. Kong, J.G. Santiago, S. Weiss, O. Bakajin, "Femtomole mixer for microsecond kinetic studies of protein folding", Anal. Chem., Vol. 76, No. 24, pp. 7169–7178, (2004).

[29] C.C. Liu, Y.N. Wang, L.M. Fu, "Micro-distillation system for formaldehydeconcentration detection", Chem. Eng. J., Vol. 304, pp. 419–425, (2016).

[30] K. Meller, M. Szumski, B. Buszewski, "Microfluidic reactors with immobilizedenzymes-Characterization dividing, perspectives", Sens. Actuators B: Chem., Vol. 244, pp. 84–106, (2017).

[31] S.A. Nabavi, G.T. Vladisavljevi´c, V. Manovi´c, Mechanisms and control ofsingle-step microfluidic generation", Chem. eng. J., Vol. 322, pp. 140-148,(2017)

[32] T. Kanai, M. Tsuchiya, "Microfluidic devices fabricated using stereolithography for preparation of monodisperse double emulsions", Chem. Eng. J., Vol. 290, pp.400–404, (2016).

[33] C.C. Liu, Y.N. Wang, L.M. Fu, D.Y. Yang, "Rapid integrated microfluidicpaper-based system for sulfur dioxide detection", Chem. Eng. J., Vol. 316, pp. 790–796, (2017).

[34] G. Foffi, A. Pastore, F. Piazza, P.A. Temussi, "Macromolecular crowding: chemistry and physics meet biology ", Phys. Biol., Vol. 10, No. 4, (2013).

[35] N.T. Nguyen, Z.G. Wu, "Micromixers - a review", J. Micromech. Microeng., Vol. 15, No. 2, pp.1–16 , (2005).

[36] Ch.Y. Lee, W.T. Wang Ch.Ch. Liuc, L.M. Fu, "Passive mixers in microfluidic systems: A review", Chem. Eng. J., Vol.  288, pp. 146–160, (2016).

[37] M. Moghimi, N. Jalali, "Design and fabrication of an effective micromixer through passive method", JCARME, Vol. 9, No. 2, pp.371-383, (2019).

[38] A. Cosentino, H. Madadi, P. Vergara, R.Vecchione, F. Causa, and P. A. Netti, “An efficient planar accordion-shaped micromixer: From biochemical mixing to biological application,” Sci. Rep., Vol. 5, No. November, pp. 1-10, (2015).

[39] C.C. Liu, Y.N. Wang, L.M. Fu, "Micro-distillation system for formaldehyde concentration detection", Chem. Eng. J., Vol. 304, pp. 419-425, (2016).

[40] H.W. Kim, J. Lim, J.W. Rhie, D.S. Kim, "Investigation of effective shear stress on endothelial differentiation of human adipose-derived stem cells with microfluidic screening device", Microelectron. Eng., Vol. 174, pp. 24-27 ,(2017).

[41] C.C. Liu, Y.N. Wang, L.M. Fu, D.Y. Yang, "Rapid integrated microfluidic paper-based system for sulfur dioxide detection", Chem. Eng. J., Vol. 316, pp. 790-796, (2017).

[42] K. Ellinas, V. Pliaka, G. Kanakaris, A. Tserepi, L.G. Alexopoulos, E. Gogolides, "Micro-bead immunoassays for the detection of IL6 and PDGF-2 proteins on a microfluidicplatform, incorporating superhydrophobic passive valves", Microelectron. Eng.,Vol. 175, pp. 73-80, (2017).

[43] J. Li, C. Liang, B. Zhang, C. Liu, "A comblike time-valve used in capillary-driven microfluidic devices", Microelectron. Eng., Vol. 173, pp. 73-80, (2017).

[44] H.W. Kim, J. Lim, J.W. Rhie, D.S. Kim, "Investigation of effective shear stress on endothelial differentiation of human adipose-derived stem cells with microfluidic screening device", Microelectron. Eng., Vol. 17, pp. 24-27, (2017).

[45] S. Herrlich, S. Spieth, S. Messner, R. Zengerle, "Osmotic micropumps for drug delivery", Adv. drug Deliv. Rev., Vol. 64, No. 14, pp. 1617-1627, (2012).

[46] M. Bayareh, M. Nazemi Ashani, A. Usefian, "Active and passive micromixers: A comprehensive review", Chem. Eng. Process., Vol. 147,107771. (2020).

[47] R. Fox, A. McDonald, Introduction to fluid mechanics, New York, Wiley. (1999).

[48] X. Chen, L. Zhang, "A review on micromixers actuated with magnetic nanomaterials". Microchim. Acta, Vol. 184: pp. 3639-3649. (2017).

[49] N.T. Nguyen, Z. Wu, "Micromixers-A review", J. Micromech. Microeng., Vol. 15, No. 2, pp.1-16. (2005)

[50] V. Hessel, H. Lowe, F. Schonfeld, "Micromixers-A review on passive and active mixing principles". Chem. Eng. Sci., Vol. 60, No. 8-9, pp. 2479-2501. (2005).

[51] D.J. Beebe, G.A. Mensing, G.M. Walker, "Physics and applications of microfluidics in biology", Ann. Rev. Biomed. Eng., Vol. 4, No. 1, pp. 261–286, (2002).

[52] J.B. Knight, A. Vishwanath, J.P. Brody, R.H. Austin, "Hydrodynamic focusing on a silicon chip: mixing nanoliters in microseconds", Phys. Rev. Lett., Vol. 80, No. 17, pp. 3863–3866, (1998).

[53] R. Hu, C. Liu, J. Xuan, Y. Xu, T. Li, B.-F. Liu, Y. Li, Y. Yang, "3D hydrodynamic flow focusing-based micromixer enables high-resolution imaging for studying the early folding kinetics of G-quadruplex", Sens. Actuatos. B Chem., Vol. 293, pp. 312–320, (2019).

[54] S. Yao, O. Bakajin, "Improvements in mixing time and mixing uniformity in devices designed for studies of protein folding kinetics", Anal. Chem., Vol. 79, No. 15, pp. 5753–5759, (2007).

[55] J.C. Maxwell, "On stresses in rarified gases arising from inequalities of temperature", Philos. Trans. R. Soc., Vol. 170, pp. 231–256, (1879).

[56] M. Smoluchowski von Smolan, "Über Wärmeleitung in verdünnten Gasen". Ann. Phys. Chem., Vol. 300, No. 1, pp. 101–130, (1898).

[57] D.E. Lee, "Development of micropump for microfluidic applications". LSU Doctoral Dissertations. 2083. (2007).

[58]  P.S. Chee, R.A. Rahim, R. Arsat, U. Hashim, P.L. Leow, "Bidirectional flow micropump based on dynamic rectification", Sens. Actuators A: Phys., Vol. 204, pp. 107-113, (2013).

[59] Y. Jian, D. Si, L. Chang, Q. Liu, "Transient rotating electromagnetohydrodynamic micropumps between two infinite microparallel plates", Chem. Eng. Sci., Vol. 134, pp. 12-22, (2015).

[60] A. Malvandi, D.D. Ganji, "Magnetohydrodynamic mixed convective flow of Al2O3–water nanofluid inside a verticalmicrotube", J. Magn. Magn. Mater., Vol. 369, pp. 132-141, (2014).

[61] M. Sheikholeslami, R. Ellahi, "Three dimensional mesoscopic simulation of magnetic field effect on natural convection of nanofluid", Int. J. Heat Mass Transf., Vol.89, pp. 799-808, (2015).

[62] O.G.W. Cassells, W.K. Hussam, G. J. Sheard, "Heat transfer enhancement using rectangular vortex promoters in confined quasi-two-dimensional magnetohydrodynamic flows", Int. J. Heat Mass Trans., Vol. 93, pp. 186-199, (2016).

[63] M. Turkyilmazoglu, "Mixed convection flow of magnetohydrodynamic micropolar fluid due to a porous heated/cooled deformable plate: Exact solutions", Int. J. Heat Mass Trans., Vol. 106, pp. 127-134, (2017).

[64] S. Siddiqa, A. Faryad, N. Begum, M.A. Hossain, R.S.R. Gorl, "Periodic magnetohydrodynamic natural convection flow of a micropolar fluid with radiation", Int. J. Thermal Sci., Vol. 111, pp. 215-222, (2017).

[65] K.R. Cramer, S. Pai, Magnetofluid Dynamics for Engineers and Applied Physicist, McGraw-Hill Book, New York, Vol. 5, No. 17, (1973).

[66] C.T. Kim , J. Lee, S. Kwon, "Design, fabrication, and testing of a DC MHD micropump fabricated on photosensitive glas", Chem. Eng. Sci., Vol. 117, pp. 210-216, (2014).

[67] M. Kiyasatfar, N. Pourmahmoud, M.M. Golzan, I. Mirzaee, "Investigation of thermal behavior and fluid motion in direct current magnetohydrodynamic pumps". Ther. Sci., Vol. 18, pp. 551-562, (2014).

[68] D. Chatterjee, S. Amiroudine, Lattice Boltzmann simulation of thermofluidic transport phenomena in a DC magnetohydrodynamic (MHD) micropump, Biomed. Microdevices, Vol. 13, pp. 147-157, (2011).

[69] M. Rivero, S. Cuevas, "Analysis of the slip condition in magnetohydrodynamic (MHD) micropumps", Sens. Actuators B: Chem., Vol. 166-167, pp. 884-892, (2012).

[70] M.I. Hasan, A.J.F. Ali, R.S. Tufah," Numerical study of the effect of channel geometry on the performance of Magnetohydrodynamic micro pump", Eng. Sci. Tech. Int. J., Vol. 20, No. 3,  pp. 982-989, (2017).

[71] M. Karmozdi, A. Salari, M.B. Shafii, "Experimental study of a novel Magneto Mercury Reciprocating (MMR) micropump, fabrication and operation", Sens. Actuators A: Phys., Vol. 194, pp. 277-284,  (2013).

[72] C. Gao, Y. Jian, "Analytical solution of magnetohydrodynamic flow of Jeffrey fluid through a circular microchannel", J. Mol. Liq., Vol. 211, pp. 803-811,  (2015).

[73] L. Zhao, F. Liu, Y. Peng, W. An, C. Sha, Z. Wang, J. Liu, H. Ye, "Researchdevelopment and key scientific and technical problems on EMHD marine oil film recovery technology", Aquat. Procedia, Vol. 3, pp. 21-28,  (2015).

[74] D. Si, Y. Jian, "Electromagnetohydrodynamic (EMHD) micropump of Jeffrey fluids through two parallel microchannels with corrugated walls", J. Phys. D: Appl. Phys., 48 (2015).

[75] G. Zhao, Y. Jian, L. Chang, M. Buren, "Magnetohydrodynamic flow of generalized Maxwell fluids in a rectangular micropump under an AC electric field", J. Magn. Magn. Mater., Vol. 387, pp. 111-117, (2015).

[76] K. Yazdani, "3D Analysis of magnetohydrodynamic (MHD) micropump performance using numerical method", J. Mech., Vol. 32, No. 1,  pp. 55-62, (2016).

[77] H. Kim, A. Astle, K. Najafi, L.P. Bernal, P. D. Washabaugh, "Anintegrated electrostatic peristaltic 18-stage gas micropump with active microvalves", J. Microelectromech. Syst., Vol. 24, No. 1, pp. 192-206, (2015).

[78] H.C. Hsieh, H. Kim, "A miniature closed-loop gas chromatography system", Lab Chip, Vol. 16, No. 6, pp. 1002-1012, (2016).

[79]  I. Lee, P. Hong, C. Cho, B. Lee, K. Chun, B. Kim, "Four-electrode micropump with peristaltic motion", Sens. Actuators A: Phys., Vol. 245, pp. 19-25, (2016).

[80] H.M Sadaghiani, A. Moazzami, "Finite element analysis of voltage effect in the mechanical behavior of diaphragm of electrostatic micro-pumps", Int. J. Adv. Biotechnol. Res., Vol. 7, pp. 1968-1980,  (2016).

[81] F.A.M. Ghazali, C.K. Mah, A. AbuZaiter, P.S. Chee, M.S.M. Ali, "Soft dielectric elastomer actuator micropump", Sens. Actuators A: Phys., Vol. 263, pp.  (2017).

[82] N.A. Hamid, B.Y. Majlis, J. Yunas, A.R. Syafeeza, Y.C. Wong, M. Ibrahim, "A stack bonded thermo-pneumatic micro-pump utilizing polyimide based actuator membrane for biomedical applications", Microsyst. Technol., Vol. 23, pp. 4037-4043, (2017).

[83] N.A. Hamid, B.Y. Majlis, J. Yunas, A.A. Hamzah, M.M. Noor, "Fabrication of thermo-pneumatic driven microactuator for fluid transport applications", Adv. Sci. Lett., Vol. 19, No. 10, pp. 2854-2859 ,(2013).

[84] K. Abi-Samra, L. Clime, L. Kong, R. Gorkin III, T.H. Kim, Y.K. Cho, M. Madou, "Thermo-pneumatic pumping in centrifugal microfluidic platforms", Microfluid. Nanofluid., Vol. 11, pp. 643-652, (2011).

[85] L.J. Yang, T.Y. Lin, "A PDMS-based thermo-pneumatic micropump with Parylene inner walls", Microelectron. Eng., Vol. 88, No. 8, pp. 1894-1897, (2011).

[86] P.S. Chee, M. Nafea, P.L. Leow, M.S.M. Ali, "Thermal analysis of wirelessly powered thermo-pneumatic micropump based onplanar LC circuit", J. Mech. Sci. Tech., Vol. 30, pp. 2659-2665, (2016).

[87] P.S. Chee, M.N. Minjal, P. L. Leow, M.S.M. Ali, "Wireless powered thermo-pneumatic micropump using frequency-controlled heater", Sens. Actuators A: Phys., Vol. 233, pp. 1-8, (2015).

[88] J. Fong, Z. Xiao, K. Takahata, "Wireless implantable chip with integrated nitinol-based pump for radio-controlled local drug delivery", Lab Chip, Vol.  1, No. 4, pp. 1050-1058, (2015).

[89] M.S.M. Ali, K. Takahata, "Wireless microfluidic control with integrated shape-memory-alloy actuators operated by field frequency modulation", J. Micromech. Microeng., Vol.  21, No. 7, (2011).

[90] F. Sassa, Y. Al-Zain, T. Ginoza, S. Miyazaki, H. Suzuki, "Miniaturized shape memory alloy pumps for stepping microfluidic transport", Sens. Actuators B: Chem., Vol. 165, pp. 157-163, (2012).

[91] T. Merzouki, A. Duval, T.B. Zineb, "Finite Element analysis of a shape memory alloy actuator for a micropump", Simul. Model. Prac. Theory, Vol.  27, pp. 112-126, (2012).

[92] J.M. Robertson, R.X. Rodriguez, L.R. Holmes Jr, P.T. Mather, E.D. Wetzel, "Thermally driven microfluidic pumping via reversible shape memory polymers", Smart Mater. Struct., Vol. 25 (2016).

[93] S. Spieth, A. Schumacher, C. Kallenbach, S. Messner, R. Zengerle, "The NeuroMedicator-a micropump integrated with silicon microprobes for drug delivery in neural research", J. Micromech. Microengi., Vol. 22, (2012).

[94] S. Spieth, A. Schumacher, T. Holtzman, P. D. Rich, D. E. Theobald, J. W. Dalley, R. Nouna, S. Messner, R. Zengerle, "An intra-cerebral drug delivery system for freely moving animals", Biomed. Microdevices, Vol. 14, pp. 799-809, (2012).

[95] D. Tripathi, A. Sharma, O.A. Bég, "Electrothermal transport of nanofluids via peristaltic pumping in a finite micro-channel: Effects of Joule heating and Helmholtz Smoluchowski velocity", Int. J. Heat Mass Tran. Col., Vol. 111, pp. 138-149, (2017).

[96] S.M. Bonk, M. Stubbe, S.M. Buehler, C. Tautorat, W. Baumann , E.D. Klinkenberg, J. Gimsa, "Design and characterization of a sensorized microfluidic cell-culture system with electro-thermal micro-pumps and sensors for cell adhesion, oxygen, and pH on a glass chip", Biosensors, Vol. 5, pp. 513-536, (2015).

[97] S.A.M. Shaegh, Z. Wang, S.H. Ng, R. Wu, H.T. Nguyen, L.C.Z. Chan, A.G.G. Toh, Z. Wang, "Plug-and-play microvalve and micropump for rapid integration with microfluidic chips", Microfluid. Nanofluid., Vol. 19, pp. 557-564, (2015).

[98] T. Sato, Y. Yamanishi, V. Cacucciolo, Y. Kuwajima, H. Shigemune, M. Cianchetti, C. Laschi, S. Maeda, "Electrohydrodynamic conduction pump with asymmetrical electrode structures in the microchannels", Chem. Lett., Vol. 46, No. 7,  pp. 950-952, (2017).

[99] W. Liu, Y. Ren, J. Shao, H. Jiang, Y. Ding, "A theoretical and numerical investigation of travelling wave induction microfluidic pumping in a temperature gradient", J. Phys. D: Appl. Phys., Vol. 47, No. 7, (2014).

[100] D.H. Yoon, H. Sato, A. Nakahara, T. Sekiguchi, S. Konishi, S. Shoji, "Development of an electrohydrodynamic ion-drag micropump using three-dimensional carbon micromesh electrodes", J. Micromech. Microeng., Vol. 24, No. 9, 095003, (2014).

[101] M.K. Russel, P.R. Selvaganapathy, C.Y. Ching, "Ion drag electrohydrodynamic (EHD) micro-pumps under a pulsed voltage", J. Electrost., Vol. 82, pp. 48-54, (2016).

[102] M.K. Russel, P.R. Selvaganapathy, C.Y. Ching, "Electrohydrodynamic injection micropump with composite gold and sngle-walled carbon nanotube electrodes", J. Microelectromech. Syst., Vol. 24, No. 5, pp. 1557-1564, (2015).

[103] M.K. Russel, S.M. Hasnain, P.R. Selvaganapathy, C.Y. Ching, "Effect of doping ferrocene in the working fluid of electrohydrodynamic (EHD) micropumps", Microfluid. Nanofluid., Vol. 20, No. 112, (2016).

[104] J. Feng, Z. Wan, W. Wen, Y. Li, Y. Tang, "Influence of chamber dimensions on the performance of a conduction micropump", J. Micromech. Microeng., Vol. 26, No. 5, (2016).

[105] D.V. Fernandes,Y.K.Suh, "Numerical simulation and design optimization of an electrohydrodynamic pump for dielectric liquids", Int. J. Heat Fluid Flow, Vol. 57, pp. 1-10, (2016).

[106] D. Tripathia, S. Bhushana, O.A. Bég, "Transverse magnetic field driven modification in unsteady peristaltic transport with electrical double layer effects", Colloids Surf. A: Physicochem. Eng. Asp., Vol. 506, pp. 32-39, (2016).

[107] Y. Li, Y. Ren, W. Liu, X. Chen, Y. Tao, H. Jiang, "On controlling the flow behavior driven by induction electrohydrodynamics in microfluidic channels", Electrophoresis, Vol. 38, No. 7,  pp. 983-995, (2017).

[108] I. Kano, "Development of an EHD micropump to generate oscillating flow at low frequencies (effect of waveform on the EHD pumping)", IEEE Trans. Ind. Appl., Vol. 48, No. 3, pp. 864-871, (2012).

[109] S.H. Sadek, F. Pimenta, F.T. Pinho, M.A. Alves, "Measurement of electroosmotic and electrophoretic velocities using pulsed and sinusoidal electric fields", Electrophoresis, Vol. 38, No. 7, pp. 1022-1037, (2017).

[110] M. Ramos-Payán, J.A. Ocaña-Gonzalez, R.M. Fernández-Torres, A. Llobera, M.Á. Bello-López, "Recent trends in capillary electrophoresis for complex samples analysis: A review", Electrophoresis, Vol. 90, No. 3, pp. 1464–1481 (2017)

[111] M. Viefhues, R. Eichhorn, "DNA dielectrophoresis: Theory and applications a review", Electrophoresis, Vol. 38, No. 11, pp. 1483-1506, (2017).

[112] D.M. Blackney, J.P. Foley, "Dual-opposite injection capillary electrophoresis: Principles and misconceptions", Electrophoresis, Vol. 38, No. 5, pp. 607-616, (2017).

[113] S.C. Lin, J.C. Lu, Y.L.Sung, C.T. Lin, Y.C. Tung, "A low sample volume particle separation device with electrokinetic pumping based on circular travellingwave electroosmosis", Lab Chip, Vol. 13, No. 15, pp. 3082-3089, (2013).

[114] S.C. Lin, Y.C. Tung, C.T. Lin, "A frequency-control particle separation device based on resultant effects of electroosmosis and dielectrophoresis", Appl. Phys. Lett., Vol. 109, No. 5, (2016).

[115] X. Fu, N. Mavrogiannis, S. Doria, Z. Gagnon, "Microfluidic pumping, routing and metering by contactless metal-based electro-osmosis", Lab Chip, Vol.15, No. 17, pp. 3600-3608, (2015).

[117] M.E. Tawfik, F.J. Diez, "Maximizing fluid delivered by bubble-free electroosmotic pump with optimum pulse voltage waveform" Electrophoresis, Vol. 38, No. 5, pp. 563-571, (2017).

[118] H.S. Gaikwad, D.N. Basu, P.K. Mondal , "Slip driven micro-pumping of binary system with a layer of non-conducting fluid under electrical double layer phenomenon", Colloids Surf. A: Physicochem. Eng. Asp., Vol. 518, pp. 166-172, (2017)

[119] M.R.H. Nobari, S. Movahed, V. Nourian, S. Kazemi, "A numerical investigation of a novel micro-pump based on the induced charged electrokinetic phenomenon in the presence of a conducting circular obstacle", J. Electrostat., Vol. 83, pp. 97-107, (2016).

[120] N. Gallah, N. Habbachi, K. Besbes, "Design and modelling of droplet based microfluidic system enabled by electroosmotic micropump", Microsyst. Technol., Vol. 23, pp. 5781–5787 (2017).

[121] V. Hoshyargar, A. Khorami, S.N. Ashrafizadeh, A. Sadeghi, "Solute dispersion by electroosmotic flow through soft microchannels", Sens. Actuators B: Chem., Vol. 255, pp. 3585-3600, (2018).

[122] K. Yoshida, T. Sato, S.I. Eom, J. Kim, S. Yokota, "A study on an AC electroosmotic micropump using a square pole – Slit electrode array", Sens. Actuators A: Phys., Vol. 265, pp. 152-160, (2017).

[123] R. Kamali, M.K.D. Manshadi, A. Mansoorifar, "Numerical analysis of nonNewtonian fluid flow in a low voltage cascade electroosmotic micropump", Microsyst. Technol., Vol. 22, No. 12, pp. 2901-2907, (2016).

[124] W. Liu, J. Shao, Y. Ren, Y. Wu, C. Wang, H. Ding, H. Jiang, Y. Ding, "Effects of discrete-electrode arrangement on traveling-wave electroosmotic pumping", J. Micromech. Microeng., Vol. 26, No. 9, (2016).

[125] R. Niu, P. Kreissl, A.T. Brown, G. Rempfer, D. Botin, C. Holm, T. Palberg, J. de Graaf, "Microfluidic pumping by micromolar salt concentrations", Soft Matter., Vol. 13, No. 7, pp. 1505-1518, (2017).

[126] N.K. Ranjit, G.C. Shit, "Entropy generation on electro-osmotic flow pumping by a uniform peristaltic wave under magnetic environment", Energy, Vol. 128, pp. 649-660, (2017).

[127] M.V. Piñón, B.C. Benítez, B. Pramanick,V.H. Perez-Gonzalez, M.J. Madou, S.O. Martinez-Chapa, H. Hwang, "Direct current-induced breakdown to enhance reproducibility andperformance of carbon-based interdigitated electrode arrays for AC electroosmotic micropumps", Sens. Actuators A: Phys., Vol. 262, pp. 10-17, (2017).

[128] S.C. Lin, Y.L. Sung, C.C. Peng, Y.C. Tung, C.T. Lin," An in-situ filtering pump for particle-sample filtration based onlow-voltage electrokinetic mechanism", Sens. Actuators B: Chem., Vol. 238, pp. 809-816, (2017).

[129] X. Li, S. Liu, P. Fan, C.F.k Werner, K. Miyamoto,T. Yoshinobu, "A bubble-assisted electroosmotic micropump for a delivery of adroplet in a microfluidic channel combined with a light-address able potentiometric sensor", Sens. Actuators B: Chem., Vol. 248, pp. 993-997, (2017).

[130] C. Huang, C. Tsou, "The implementation of a thermal bubble actuated microfluidic chip with microvalve, micropump and micromixer", Sens. Actuators A, Vol. 210, pp. 147-156, (2014).

[131] W. Li, C. Tsou, "Study of different cross-shaped microchannels affecting thermal bubble-actuated microparticle manipulation", J. Micro/Nanolith. MEMS MOEMS, Vol. 14, No. 4, (2015).

[132] W.F. Fang, A.P. Lee, "CAT pump optimization for an integrated microfluidic droplet generator", Microfluid. Nanofluid., Vol.18, pp. 1265-1275, (2015).

[133] Y. Yi, A. Zaher, O. Yassine, J. Kosel, I.G. Foulds, "A remotely operated drug delivery system with an electrolytic pump and a thermoresponsive valve", Biomicrofluidics., Vol. 9, No. 5, (2015).

[134] R. Safavieh, A. Tamayol, D. Juncker, "Serpentine and leading-edge capillary pumps for microfluidic capillary systems", Microfluid. Nanofluid., Vol.18, pp. 357-366, (2015). 

[135] A. Oskooeia, A. Günther, "Bubble pump: scalable strategy for in-plane liquid routing", Lab Chip, Vol. 15, No. 13, pp. 2842-2853, (2015).

[136] B. Liu, J. Sun, D. Li, J. Zhe,· K.W. Oh, "A high flow rate thermal bubble‑driven micropumpwith induction heating", Microfluid. Nanofluid. Vol.20, (2016).

[137] X.Y. Peng, "A one-square-millimeter compact hollow structure for microfluidic pumping on an all-glass chip", Micromachines, Vol 7, No. 4,  (2016).

[138] J. Xiang, Z. Cai, Y. Zhang, W. Wang, "A micro-cam actuated linear peristaltic pump for microfluidic applications", Sens. Actuators A: Phys., Vol. 251, pp. 20-25, (2016).

[139] Y. Qu, J. Zhou, "Lumped parameter model and numerical model of vapor bubble–driven valve-less micro-pump", Adv. Mech. Eng., Vol. 9, No. 4, pp. 1-7, (2017).

[140] S. Kalinowski, S. Koronkiewicz, "Double-beam photometric direct-injection detector formulti-pumping flow system", Sens. Actuators A: Phys., Vol. 258, pp. 146-155, (2017).

[141] D.A. Boy, F. Gibou, S. Pennathur, "Simulation tools for lab on a chip research: advantages, challenges, and thoughts for the future", Lab Chip, Vol. 8, No. 9, pp. 1424-1431, (2008).

[142] M. Gad-el-Hak, MEMS: Introduction and Fundamentals,  CRC Press,(2005).

[143] P. Deuflhard, J. Hermans, B. Leimkuhler, A.E. Mark, S. Reich, R.D. Skeel, R.D. (Eds.) Computational Molecular Dynamics: Challenges, Methods, Ideas, Springer-Verlag Berlin Heidelberg Press. (1999).

[144] M. Nasiri, S, Abdi, Introduction to the simulation of Dissipative Particle Dynamics (DPD), Semnan university Press, in Persion, (2020).

[145] J. Atencia, J. Morrow, L.E. Locascio, "The microfluidic palette: A diffusive gradient generator with spatio-temporal control", Lab Chip, Vol.9, No.18, pp. 2707–2714, (2009).

[146]  V.V. Abhyankar, M.A. Lokuta, A. Huttenlocher, D.J. Beebe, "Characterization of a membrane-based gradient generator for use in cell-signaling studies", Lab Chip, Vol.6, No. 3, pp. 389–393, (2006).

[147] D. Kim, M. A. Lokuta, A. Huttenlocher and D. J. Beebe, "Selective and tunable gradient device for cell culture and chemotaxis study", Lab Chip, Vol. 9, No. 12, pp.1797–1800, (2009).

[148] S. Kim, H. Joon Kimz, N.L. Jeon, "Biological applications of microfluidic gradient devicesw", Integr. Biol., Vol. 2, No. 11-12, pp. 584–603, (2010).

[149] A.S. Chaurasia, F. Jahanzad, S. Sajjadi, "Flexible microfluidic fabrication of oilencapsulated alginate microfibers". Chem. Eng. J., Vol. 308: pp. 1090–1097, (2017).

[150] B.D. Gates, Q. Xu, M. Stewart, D. Ryan, C.G. Willson, G.M. Whitesides, "New approachesto nanofabrication: molding, printing, and other techniques". Chem. Rev., Vol. 105, No. 4, pp. 1171-1196, (2005).

[151] D.R. Reyes, D. Iossifidis, P.A. Auroux, A. Manz, "Micro total analysis systems. 1.Introduction, theory, and technology". Anal. Chem., Vol. 74, No. 12, pp. 2623-2636. (2002).

[152] M.W. Toepke, M.W.T. Kenis, "Multilevel Microfluidics via Single-Exposure Photolithography",J. Am. Chem. Soc., Vol. 127, No. 21, pp. 7674–7687,( 2005).

[153] B. Hannes, J. Vieillard, E.B. Chakra, R. Mazurczyk, C.D. Mansfield, J. Potempa, S. Krawczyk, "The etching of glass patterned by microcontact printing with application to microfluidics and electrophoresis", Sens. Actuators B, Vol. 129, No. 1, pp. 255–262,( 2008).

[154] L.A. Tse, P.J. Hesketh, D.W. Rosen, J.L. Gole, "Stereolithography on silicon for microfluidics and microsensor packaging", Microsyst. Technol., Vol. 9, No. 5, pp. 319–323,( 2003).

[155] T. Saitoh,Y. Suzuki, M. Hiraide, "Preparation of Poly(N-isopropylacrylamide)-Modified Glass Surface for Flow Control in Microfluidics" ,Anal. Sci.,Vol. 18, No. 2, pp. 203–205,(2002).

[156] C.F. Carlborg, T. Haraldsson, K. Oberg, M. Malkoch, W. van der Wijngaart" Beyond PDMS: off-stoichiometry thiol–ene (OSTE) based soft lithography for rapid prototyping of microfluidic devices", Lab Chip, Vol. 11, No. 18, pp. 3136–3147, (2011).

[157] J. Cai, J. Jiang, F. Gao, G. Jia, J Zhuang, G. Tang, Y. Fan, " Rapid prototyping of cyclic olefin copolymer based microfluidic system with CO2 laser ablation", Microsyst. Technol, Vol. 23, No. 10: pp. 5063–5069, (2017).

[158] X. Wang, C. Liedert, R. Liedert, I. Papautsky" A disposable, roll-to-roll hot-embossed inertial microfluidic device for size-based sorting of microbeads and cells",  Lab Chip.,Vol 16, No. 10, pp. 1821–1830, (2016).

[159] K. Iwai, K.C. Shih, X. Lin, T.A. Brubaker, R.D. Sochol, L.W. Lin, "A self-sufficient pressure pump using latex balloons for microfluidic applications",  Lab Chip, Vol. 14, No. 19,  pp. 3790–379, (2014).

[160] L. Gatti, M. Cecconi, J.L. Dewandel, J. Becker, "Optical Tomograph based on holographic interferometry for fluid research on the International Space Station", AIP Conf. Proc.,Vol. 504. No. 1. pp. 330–335, (2000).

[161] N.T. Nguyen, X. Huang, "Miniature valveless pumps based on printed circuit board technique", Sens. Actuators A, Vol. 88, No. 2, pp. 104–111, (2001).

[162] M. Rhee, M.A. Burns, "Microfluidic assembly blocks", Lab Chip,Vol. 8, No. 8, pp. 1365–1373,( 2008).

[163] S. Dekker, W. Buesink, M. Blom, M. Alessio, N. Verplanck, M. Hihoud, C. Dehan, W. Cesar, A.L. Nel, A. van den Berg, "Standardized and modular microfluidic platform for fast Lab on Chip system development", Sens. Actuators B: Chem., Vol. 272, pp.468-478 ,(2018).

[164] D.I. Walsh, D.S. Kong, S.K. Murthy, P.A. Carr, "Enabling microfluidics: from clean rooms to makerspaces". Trends Biotechnol, Vol. 35: pp. 383–392. (2017).

[165] V. Faustino, S.O. Catarino, R. Lima, G. Minas, "Biomedical microfluidic devices by using low-cost fabrication techniques: A review:. J. Biomech., Vol. 49, pp. 2280–2292. (2016)

[166] J. Giboz, T. Copponnex, P. Mélé, "Microinjection molding of thermoplastic polymers: A review". J. Micromech. Microeng., Vol. 17, No. 6, pp. 96-109. (2007)

[167] K.M. Weerakoon-Ratnayake, C.E. O'Neil, F.I. Uba, S.A. Soper, "Thermoplastic nanofluidic devices for biomedical applications", Lab Chip, Vol. 17, No. 3, pp. 362–381. (2017)

[168] S. Waheed, J.M. Cabot, N.P. Macdonald, T. Lewis, R.M. Guijt, B. Paull, M.C. Breadmore, "3D printed microfluidic devices: Enablers and barriers". Lab Chip, Vol. 16, No. 11, pp. 1993–2013. (2016).

[169] L.R. Harriott,  "Limits of lithography". Proc. IEEE, Vol. 89, No. 3, pp. 366–374. (2001).

[170] E. Zolotoyabko ,  Diffraction phenomena in optics. In basics concepts of X-ray diffraction, John Wiley & Sons, Inc.: Hoboken, NJ, USA(2014).

[171] H.T. Chang, C.Y. Lee, C.Y. Wen, "Design and modeling of electromagnetic actuator in MEMS-based valveless impedance pump", Microsyst. Technol., Vol. 13, pp. 1615-1622, (2007).

[172] H.T. Chang, C.Y. Wen, C.Y. Lee, "Design, analysis and optimization of an electromagnetic actuator for a micro impedance pump", J. Micromech. Microeng., Vol.19 (2009).

[173] M. Matar, A.T. Al-Halhouli1, A. Dietzel, S. Büttgenbach, "Microfabricated centrifugal pump driven by an integrated synchronous micromotor", Microsyst. Technol., Vol. 23, pp. 2475-2483, (2017).

[174] X. Li, D. Li, X. Liu, H. Chang, "Ultra-monodisperse droplet formation using PMMA microchannels integrated with low-pulsation electrolysis micropumps", Sens. Actuators B: Chem., Vol. 229, pp. 466-475, (2016).

[175] S.C. Lin, Y.L. Sung, C.C. Peng, Y.C. Tung, C.T. Lin, "An in-situ filtering pump for particle-sample filtration based on low-voltage electrokinetic mechanism", Sens. Actuators B: Chem., Vol. 2, pp. 809-816, (2017).

[176] F. Opekar, K. Nesměrák, P. Tuma, "Electrokinetic injection of samples into a short electrophoretic capillary controlled by piezoelectric micropumps", Electrophoresis, Vol. 37, No. 4, pp. 595-600, (2016).

[177] G.P. Kanakaris, N. Fatsis-Kavalopoulos, L.G. Alexopoulos, "Laser activated single-use micropumps". Sens. Actuators B: Chem., Vol. 220, pp. 549-556, (2015).

[178] W.J. Spencer, W.T. Corbett, L.R. Dominguez, B.D. Shafer. "An electronically con- trolled piezoelectric insulin pump and valves", IEEE Trans. Sonics. Ultrason., Vol. 25, No. 3, pp. 153–156, (1978).

[179] B. Pe čar, M. Mo ž ek, D. Resnik, T. Dol ž an, D.  Vrta čnik, D. Kri ž aj. "Piezoelectric peristaltic micropump with a single actuator", J. Micromech. Microeng., Vol. 24, No. 10, 105010, (2014) .

[180] Y.H. Wang, Y.W Tsai, Ch.H. Tsai, Ch.Y. Lee, L.M. Fu, "Design and analysis of impedance pumps utilizing electromagnetic actuation". Sensors, Vol. 10, No. 4, pp. 4040–4052, (2010) .

[181] J. Ni, B. Wang, S. Chang, Q. Lin, "An integrated planar magnetic micropump", Microelectron. Eng., Vol. 117:pp. 35–40, (2014) .

[182] T.Y. Lin, Y.C. Ou, L.J. Yang, "A thermopneumatic valveless micropump with PDM- S-based nozzle/diffuser structure for microfluidic system".
Proc. ASME Micro Nanoscale Heat Mass Transf. Int. Conf ., pp. 293-296, (2009)

[183] H.H. Liao, Y.J. Yang, "Fabrication and characterization of thermo-pneumatic peri- staltic micropumps". Nanotech., Vol. 3, pp.296–299, (2008) .

[184]  Y.J. Yang, H.H. Liao, "Development and characterization of thermopneumatic peri- staltic micropumps", J. Micromech. Microeng., Vol. 19, No. 2, (2009) .

[185] P.S. Chee, M.N. Minjal, P.L. Leow, M.S.M Ali, "Wireless powered thermo-pneumatic mi- cropump using frequency-controlled heater", Sens. Actuators A Phys., Vol. 233, pp. 1–8, (2015) .

[186] B. Liu, J. Sun, D. Li, J. Zhe, K.W. Oh, "A high flow rate thermal bubble-driven micropump with induction heating". Microfluid. Nanofluidics, Vol. 20, No. 11, pp. 1–9, (2016) .

[187] N.A. Hamid, B.Y. Majlis, J. Yunas, A.R. Syafeeza, Y.C. Wong, M. Ibrahim, "A stack bonded thermo-pneumatic micro-pump utilizing". Microsyst. Technol., Vol. 23, pp. 4037–43(2017).

[188] H.H. Kim, D.H. Park, B.H. Ryu , K.J. Lim, "Design and modeling of piezoelectric pump for microfluid devices". Ferroelectrics, Vol. 378, No. 1, pp. 92–100, (2009) .

[189] H.K. Ma, W.F. Luo, J.Y. Lin, "Development of a piezoelectric micropump with novel separable design for medical applications", Sens. Actuators A Phys., Vol. 236, pp.57–66, (2015) .

[190] H.K. Ma, R.H. Chen, N.S. Yu, Y.H. Hsu, "A miniature circular pump with a piezoelectric bimorph and a disposable chamber for biomedical applications, Sens. Actuators A Phys., Vol. 251, pp. 108–18 (2016) .

[191] T.T. Nguyen, N.S. Goob, V.K. Nguyenc, Y. Yood, S. Park, "Design, fabrication, and exper- imental characterization of a flap valve IPMC micropump with a flexibly supported diaphragm". Sens. Actuators A Phys., Vol. 141, No. 2, pp. 640–648, (2008) .

[192] P.S. Chee, K.M. Che, M. Sultan, M. Ali, Soft dielectric elastomer actuator for microp- ump application, 2016 IEEE 29th Int. Conf. Micro Electro Mech. Syst. (MEMS), pp. 561–564. (2016).

[193] R. Kant, D. Singh, S. Bhattacharya,  "Digitally controlled portable micropump for trans- port of live micro-organisms", Sens. Actuators A Phys,. Vol. 265, pp.138–51,(2017) .

[194] M. Shen, L. Dovat, M.A.M. Gijs,  "Magnetic active-valve micropump actuated by a ro- tating magnetic assembly", Sens. Actuators B Chem., Vol. 154, No. 1, pp. 52–58, (2011)

[195] A.H. Sima, A. Salari, M.B. Shafii,  "Low-cost reciprocating electromagnetic-based mi- cropump for high-flow rate applications.", J. Micro. Nanolithogr. MEMS MOEMS, Vol. 14, No. 3, 035003, (2015).

[196] J. Ni, B. Wang, S. Chang, Q. Lin, "An integrated planar magnetic micropump", Microelectron. Eng., Vol. 117, pp. 35-40, (2014).

[197] W. Hilber, S. Clara, B. Jakoby," Microfluidic pumping utilizing a PDMS membrane with an integrated nonuniform open-porous foam", IEEE Sens. J., Vol.15, No. 9, pp. 5109-5114, (2015).

[198] N.Q. Dich, T.X. Dinh, P.H. Pham, V.T. Dau, "Study of valveless electromagnetic micropump by volume-of-fluid and OpenFOAM", Jap. J. Appl. Phys., Vol. 54, No. 5, (2015).

[199] M.M. Said, J. Yunas, B. Bais, A.A. Hamzah, B.Y. Majlis, "Hybrid polymer composite membrane for anelectromagnetic (EM) valveless micropump", J. Micromech. Microeng. Vol. 27, No. 7, (2017).

[200] D.J. Thomas, Z. Tehrani, B. Redfearn, "3-D printed composite microfluidic pump for wearable biomedical applications", Addit. Manuf., Vol. 9, pp. 30-38 (2016).

[201] D. Tripathi, R. Jhorar, O.A. Bég, A. Kadir, "Electro-magneto-hydrodynamic peristaltic pumping of couple stress biofluids through a complex wavy micro-channel", J. Mol. Liq., Vol. 236, pp. 358-367 (2017).

[202] M.M.. Said, J.Yunas, R.E. Pawinanto, B.Y. Majlis, B. Bais, "PDMS based electromagnetic actuator membrane with embedded magnetic particles in polymer composite", Sens. Actuators A: Phys., Vol. 245, pp. 85-96, (2016).

[203] S.D. Kim, H.J. Kim, N.L. Jeon, "Biological applications of microfluidic gradient devices", Integr. Biol., Vol. 2, No. 11-12, pp. 584–603, (2010).

[204] B.G. Chung, J.B. Choo, "Microfluidic gradient platforms for controlling cellular behavio"r, Electrophoresis, Vol.  31, No. 18, pp. 3014–3027, (2010).

[205] S.J. Wang, W. Saadi, F. Lin, C.M.C. Nguyen, N.L. Jeon, "Differential effects of EGF gradient profiles on MDA-MB-231 breast cancer cell chemotaxis", Exp. Cell Res., Vol. 300, No. 1, pp. 180–189, (2004).

[206] V.V. Abhyankar, M.W. Toepke, C.L. Cortesio, M.A. Lokuta, A. Hutenlocher, D.J. Beebe, "A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment", Lab Chip, Vol. 8, No. 9, pp. 1507–1515, (2008).

[207] N.L. Jeon, H. Baskaran, S.K.W. Dertinger, G.M. Whitesides, Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device, Nat. Biotechnol., Vol. 20, pp. 826–830, (2002).

[208] F. Lin, C.M.C. Nguyen, S.J. Wang, W. Saadi, S.P. Gross, N.L. Jeon, "Effective neutrophil chemotaxis is strongly influenced by mean IL-8 concentration", Biochem. Biophys. Res. Commun., Vol. 319, No. 2, pp. 576–581, (2004).

[209] S.K.W. Dertinger, X.Y. Jiang, Z.Y. Li, V.N. Murthy, G.M. Whitesides, "Gradients of substrate-bound laminin orient axonal specification of neurons", Proc. Natl. Acad. Sci. USA.,Vol. 99, No. 20, pp. 12542–12547, (2002).

[210] B.G. Chung, L.A. Flanagan, S.W. Rhee, P.H. Schwartz, A.P. Lee, E.S. Monuki, N.L. Jeon, "Human neural stem cell growth and differentiation in a gradient-generating microfluidic device", Lab Chip, Vol. 5, No. 4, pp. 401– 406, (2005).

[211] O.C. Amadi, M.L. Steinhauser, Y. Nishi, S. Chung, R.D. Kamm, A.P. McMahon, R.T. Lee, "A low resistance microfluidic system for the creation of stable concentration gradients in a defined 3D microenvironment", Biomed. Microdevices, Vol. 12, pp. 1027–1041, (2010).

[212] I. Barkefors, S. Le Jan, L. Jakobsson, E. Hejll, G. Carlson, H. Johansson, J. Jarvius, J.W. Park, N.L. Jeon, J. Kreuger, "Endothelial cell migration in stable gradients of vascular endothelial growth factor a and fibroblast growth factor 2-Effects on chemotaxis and chemokinesis", J. Biol. Chem., Vol. 283, No. 20, pp. 13905–13912, (2008).

[213]  A. Shamloo, N. Ma, M.M. Poo, L.L. Sohn, S.C. Heilshorn, "Endothelial cell polarization and chemotaxis in a microfluidic device", Lab Chip, Vol. 8, No. 8, pp. 1292–1299, (2008).

[214] N.T. Nguyen: Micromixers, Second edition (2012).

[215] K. Fluri, G. Fitzpatrick, N. Chiem, D.J. Harrison, "Integrated capillary electrophoresis devices with an efficient postcolumn reactor in planar quartz and glass chips", Anal. Chem., Vol. 68, No. 23, pp. 4285–4290, (1996).

[216] N.Y. Lee, M. Yamada, M. Seki, "Development of a passive micromixer based on repeated fluid twisting and flattening, and its application to DNA purification", Anal. Bioanal. Chem., Vol. 383, pp. 776–782, (2005).

[217] H.Y. Lee, J. Voldman, "Optimizing micromixer design for enhancing dielectrophoretic microconcentrator performance", Anal. Chem., Vol. 79, No. 5, pp. 1833–1839, (2007).

[218] A. Murakami, M. Nakaura, Y. Nakatsuji, S. Nagahara, Q. Tran-Cong, K. Makino, "Fluorescent-labeled oligonucleotide probes: detection of hybrid formation in solution by fluorescence polarization spectroscopy", Nucleic Acids Res., Vol. 19, No. 15, pp. 4097–4102, (1991).

[219] Q.H. Wan, X.C. Le, "Studies of Protein−DNA interactions by capillary electrophoresis/ laser-induced fluorescence polarization", Anal. Chem., Vol. 72, No. 22, pp. 5583–5589, (2000).

[220] D. Gerber, S.J. Maerkl, S.R. Quake, "An in vitro microfluidic approach to generating protein-interaction networks", Nat. Methods, Vol.6, (2008).

[221] Y. Li, F. Xu, C. Liu, Y.Z. Xu, X.J. Feng, B.F. Liu," A novel microfluidic mixer based on dual-hydrodynamic focusing for interrogating the kinetics of DNA-protein interaction", Analyst, Vol. 138, No. 16, pp. 4475–4482, (2013).

[222] C. Gasc, E. Peyretaillade, P. Peyret, "Sequence capture by hybridization to explore modern and ancient genomic diversity in model and nonmodel organisms", Nucleic Acids Res., Vol. 44, No. 10, pp. 4504–4518, (2016).

[223] Y. Mianzhi, N.P. Shah, "Contemporary nucleic acid-based molecular techniques for detection, identification, and characterization of Bifidobacterium", Crit. Rev. Food Sci. Nutr., Vol. 57, No. 5, pp. 987–1016, (2017).

[224] R.H. Liu, R. Lenigk, R.L. Druyor-Sanchez, J.N. Yang, P. Grodzinski, "Hybridization enhancement using cavitation microstreaming", Anal. Chem., Vol. 75, No. 8, pp. 1911–1917, (2003).

[225] H.S. Abadi, M. Packirisamy, R. Wüthrich, "High performance cascaded PDMSmicromixer based on split-and-recombination flows for lab-on-a-chipapplications", RSC Adv., Vol. 3, No. 20, pp. 7296–7305, (2013).

[226] M. Bezagu, S. Arseniyadis, J. Cossy, O. Couture, M. Tanter, F. Monti, P.Tabeling, "A fast and switchable microfluidic mixer based onultrasound-induced vaporization of perfluorocarbon", Lab Chip, Vol. 15, No.9, pp. 2025–2029, (2015).

[227] A. Bohr, J. Boetker, Y. Wang, H. Jensen, J. Rantanen, M. Beck-Broichsitter, "High-throughput fabrication of nanocomplexes using 3D-printedmicromixers", J. Pharm. Sci., Vol. 106, No. 3, pp. 835–842, (2017).

[228] G. Santillo, F.A. Deorsola, S. Bensaid, N. Russo, D. Fino, "MoS2 nanoparticle precipitation in turbulent micromixers", Chem. Eng. J., Vol. 207–208, pp. 322–328, (2012).

[229] F.T.G. van den Brink, T. Wigger, L. Ma, M. Odijk, W. Olthuis, U. Karstb, A. vanden Berg, "Oxidation and adduct formation of xenobiotics in a microfluidicelectrochemical cell with boron doped diamond electrodes and anintegrated passive gradient rotation mixer", Lab Chip, Vol. 16, No. 20, pp. 3990–4001, (2016).

[230] F.G. Ergin, B.B. Watz, K. Erglis, A. Cebers, "Time-resolved velocity measurements in a magnetic micromixer", Exp. Therm. Fluid Sci., Vol.67, pp. 6–13, (2015).

[231] G.T. Vladisavljevi´c, R.A. Nuumani, S.A. Nabavi, "Microfluidic production of multiple emulsions", Micromachines, Vol. 8, No. 3, (2017).

[232] K.W. Oh "Lab-on-chip (LOC) devices and microfluidics for biomedical applications". MEMS Biomed. Appl., pp.150–71, (2012).

[233] W. Zhang, R.E. Eitel, "An integrated multilayer ceramic piezoelectric micropump for microfluidic systems". J. Intell. Mater. Syst. Struct., Vol. 24, No. 13, pp. 1637–1646,( 2013).

[234] Y.H. Wang, Y.W. Tsai, C.H. Tsai, C.Y. Lee, L.M. Fu, "Design and analysis of impedance pumps utilizing electromagnetic actuation". Sens., Vol. 10, No. 4, 404052 ,(2010).

[235] S.M. Ha, W. Cho, Y. Ahn, "Disposable thermo-pneumatic micropump for bio lab-on-a-chip application". Microelectron. Eng., Vol. 86, No. 4–6, pp. 1337–9,( 2009) .

[236] N.A. Hamid, Y.M. Burhanuddin, Y. Jumril, A.R. Syafeeza, Y.C. Wong, M. Ibrahim, "A stack bonded thermo-pneumatic micro-pump utilizing polyimide based actuator mem- brane for biomedical applications". Micros. Tech., Vol. 23, No. 9, pp. 4037–43,( 2017).

[237] W.H. Chang, S.Y. Yang, C.H. Wang, M.A. Tsai, P.C. Wang, T.Y. Chen, S.C. Chen, G.B. Lee, "Rapid isolation and detection of aquaculture pathogens in an integrated microfluidic system using loop-mediated isothermal amplification", Sens. Actuators B: Chem., Vol. 180, pp.  96-106, (2013).

[238] C.H. Wang, C.J. Chang, J.J. Wu, G.B. Lee, "An integrated microfluidic device utilizing vancomycin conjugated magnetic beads and nanogold-labeled specific nucleotide probes for rapid pathogen diagnosis", Nanomedicine, Vol. 10, No. 4, pp.809-818, (2014).

[239] W.H. Chang, C.H. Wang, C.L. Lin, J.J. Wu, M.S. Lee, G.B. Lee, "Rapid detection and typing of live bacteria from human joint fluid samples by utilizing an integrated microfluidic system", Biosens. Bioelectron., Vol. 66, pp.148-154, (2015).

[240] C.Y. Chao, C.H. Wang, Y.J. Che, C.Y. Kao, J.J. Wu, G.B. Lee, "An integrated microfluidic system for diagnosis of there sistance of Helicobacter pylori to quinolone-based antibiotics", Biosens. Bioelectron., Vol. 78, pp. 281-289, (2016).

[241] Y.T.Tseng, C.H. Wang, C.P. Chang, G.B. Lee, "Integrated microfluidic system for rapid detection of influenza H1N1 virus using a sandwich-based aptamer assay", Biosens. Bioelectron., Vol. 82 , pp.105-111, (2016).

[242] W.B. Lee, C.Y. Fu, W.H. Chang, H.L. You, C.H.Wang, M.S. Lee, G.B. Lee, "A microfluidic device for antimicrobial susceptibility testing based on a broth dilution method", Biosens. Bioelectron., Vol. 87, pp. 669-678, (2017).

[243] S.L. Chen, W.H. Chang, C.H. Wang, H.L. You, J.J. Wu, T.H. Liu, M. S. Lee, G.B. Lee, "An integrated microfluidic system for live bacteria detection from human joint fluid samples by using ethidium monoazide and loop-mediated isothermal amplification", Microfluid. Nanofluid., Vol. 21 (2017).

[244] D. Bogojevic, M.D. Chamberlain, I. Barbulovic-Nad, A.R. Wheeler, "A digital microfluidic method for multiplexed cell-based apoptosis assays", Lab Chip, Vol. 12, No. 3, pp. 627-634, (2012).

[245] I.A. Eydelnant, U. Uddayasankar, B.Y. Li, M.W.Liao, A.R.Wheeler, "Virtual microwells for digital microfluidic reagent dispensing and cell culture",  Lab Chip, Vol. 12, No. 4, pp. 750-757, (2012).

[246] D.G. Rackus, M.H. Shamsi, A.R. Wheeler, "Electrochemistry, biosensors and microfluidics: a convergence of fields", Chem. Soc. Rev., Vol. 44, No. 15, pp. 5320-5340,(2015).

[247] A.H.C. Ng, B. Betty Li, M.D. "Chamberlain, A.R. Wheeler, Digital Microfluidic Cell Culture", Annu. Rev. Biomed. Eng., Vol. 17 ,pp. 91-112, (2015).

[248] D.G. Rackus, R.P.S. de Campos, C. Chan, M.M. Karcz, B. Seale, T. Narahari, C. Dixon, M.D. Chamberlain, A.R. Wheeler, "Pre-concentration by liquid intake by paper (PCLIP): a new technique for large volumes and digital microfluidics", Lab Chip, Vol. 17, No. 13, pp. 2272-2280, (2017).

[249] L.M. Przybyla, J. Voldman, "Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal", Proc. Nat. Acad. Sci. USA, Vol. 109, No. 3, pp. 835-840, (2012).

[250] T. Zhou, J. Yang, D. Zhu, J. Zheng, S. Handschuh-Wang, X. Zhou, J. Zhang, Y. Liu, Z. Liu, C. He, X. Zhou, "Hydrophilic sponges for leaf-inspired continuous pumping of liquids", Adv. Sci., Vol. 4 , No. 6, 1700028, (2017).

[251] Z. Ma, Y. Zheng, Y. Cheng, S. Xie, X. Ye, M. Yao, "Development of an integrated microfluidic electrostatic sampler for bioaerosol", J. Aerosol Sci., Vol. 95, pp. 84-94, (2016).

[252] R. Kant, D. Singh, S. Bhattacharya, "Digitally controlled portable micropump for transport of live micro-organisms", Sens. Actuators A: Phys., Vol. 265, pp. 138-151, (2017).

[253] S.A.M. Shaegh, A. Pourmand, M. Nabavinia, H. Avci, A. Tamayol, P. Mostafalu, H.B. Ghavifekr, E.N. Aghdam, M.R. Dokmeci, A. Khademhosseini, Y.S. Zhang, "Rapid prototyping of whole-thermoplastic microfluidics with built-inmicrovalves using laser ablation and thermal fusion bonding", Sens. Actuators B: Chem., Vol. 255 , pp. 100-109 ,(2018).

[254] M.J. Jebrail, A. Sinha, S. Vellucci, R.F. Renzi, C. Ambriz, C. Gondhalekar, J.S. Schoeniger, K.D. Patel, S.S. Branda, "World-to-digital-microfluidic interface enabling extraction and purification of RNA from human whole blood", Anal. Chem., Vol. 86, No. 8, pp. 3856-3862, (2014).

[255] R.M. Feeny, N.L. Puissant, C.S. Henry, "Degassed PDMS pump for controlled extraction from dried filter samples in microfluidic devices", Anal. Methods, Vol. 8, No.47, pp. 8266-8271, (2016).

[256] S. Zehnle, F. Schwemmer, G. Roth, F. von Stetten, R. Zengerleabc, N. Paust, "Centrifugo-dynamic inward pumping of liquids on a centrifugal microfluidic platform", Lab Chip, Vol. 12, No. 24, pp. 5142-5145, (2012).

[257] F. Schwemmer, S. Zehnle, D. Mark, F. von Stetten, R. Zengerle, N. Paust, "A Microfluidic timer for timed valving and pumping in centrifugal microfluidics". Lab Chip, Vol. 15, No. 6, pp. 1545-1553, (2015).

[258] Y. Song, M. Li, X. Pan, Q. Wang, D. Li, "Size-based cell sorting with a resistive pulse sensor and an electromagnetic pump in a microfluidic chip", Electrophoresis, Vol. 36, No. 3, pp. 398-404, (2015).

[259] R. Kant, H. Singh, M. Nayak, S. Bhattacharya, "Optimization of design and characterization of a novel micro-pumping system with peristaltic motion", Microsyst. Technol., Vol.19, pp. 563-575, (2013).

[260] F.G. Strobl, D. Breyer, P. Link, A.A. Torrano , C. Bräuchle, M.F. Schneider, A.Wixforth, "A surface acoustic wave-driven micropump for particle uptake investigation under physiological flow conditions in very small volumes", Beilstein J. Nanotechnol., Vol. 6, pp. 414-419, (2015).

[261] M.K.D. Manshadi , D, Khojasteh, M. Mohammadi, R. Kamali, "Electroosmotic micropump for lab-on-a-chip biomedical applications", Int. J. Numer. Model., Vol. 29, No. 5, pp. 845-858, (2016).

[262] K. Wang, R. Liang, H. Chen, S. Lu, S. Jia, W. Wang, "A microfluidic immunoassay system on a centrifugal platform", Sens. Actuators B: Chem., Vol. 251, pp. 242-249, (2017).

[263] N. Kumar, D. George, P. Sajeesh, P.V. Manivannan, A.K. Sen, "Development of a solenoid actuated planar valveless micropump with single and multiple inlet– outlet arrangements", J. Micromech. Microeng., Vol. 26, No. 7, (2016).

[264] Z. Cai, J. Xiang, H. Chen, W. Wang, Membrane-based valves and inward-pumping system for centrifugal microfluidic platforms, Sens. Actuators B: Chem., Vol. 228, pp. 251-258, (2016).

[265] I. Ortiz-Rivera , T.M. Courtne , A. Sen, Enzyme Micropump-Based Inhibitor Assays, Adv. Funct. Mater., Vol. 26, No. 13, pp. 2135-2142, (2016).

[266] S. Kalinowski, S. Koronkiewicz, "Double-beam photometric direct-injection detector formulti-pumping flow system", Sens. Actuators A: Phys., Vol. 258, pp. 146-155, (2017).

[267] A. Cobo, R. Sheybani, H. Tu, E. Meng, "A wireless implantable micropump for chronic drug infusion against cancer", Sens. Actuators A: Phys., Vol. 239, pp. 18-25, (2016).

[268] R. Sheybani, A. Cobo, E. Meng, "Wireless programmable electrochemical drug delivery micropump with fully integrated electrochemical dosing sensors", Biomed. Microdevices, Vol. 17, (2015).

[269] S. Sengupta, D. Patra, I. Ortiz-Rivera, A. Agrawal, S. Shklyaev, K. K. Dey, U. Cordova-Figueroa, T. E. Mallouk, A. Sen, "Self-powered enzyme micropumps", Nat. Chem., Vol. 6, pp. 415-422, (2014).

[270] I. Ortiz-Rivera, H. Shum, A. Agrawal, A. Sen and A. C. Balazs, "Convective flow reversal in self-powered enzyme micropumps", Proc. Natl. Acad. Sci. USA, Vol. 113, No. 10, pp. 2585-2590, (2016).

[271] H. Zhang, W.T. Duan, M. Q. Lu, X. Zhao, S. Shklyaev, L. Liu, T.J. Huang, A. Sen, "Self-powered glucose-responsive micropumps", ACS. Nano., Vol. 8, No. 8, pp. 8537-8542, (2014).

[272] L. Valdez, H. Shum, I. Ortiz-Rivera, A.C. Balazs, A. Sen, "Solutal and thermal buoyancy effects in self-powered phosphatase micropumps", Soft. Matter., Vol. 13, No. 15, pp. 2800-2807, (2017).

[273] P. Song, S. Kuang, N. Panwar, G. Yang, D.J.H. Tng, S.C. Tjin, W.J. Ng, M.B.A. Majid, G. Zhu, K.T. Yong, Z.L. Wang, "A self-powered implantable drug-delivery system using biokinetic energy", Adv. Mater., Vol. 29, No. 11, (2017).

 

[274] N. Okura, Y. Nakashoji, T. Koshirogane, M. Kondo, Y. Tanaka, K. Inoue, M. Hashimoto, "A compact and facile microfluidic droplet creation device using a piezoelectric diaphragm micropump for droplet digital PCR platforms", Electrophoresis, Vol.38, No. 20, pp. 2666-2672, (2017).

[275] Y. Nakashoji, H. Tanaka, K. Tsukagoshi, M. Hashimoto, "A poly(dimethylsiloxane) microfluidic sheet reversibly adhered on a glass plate for creation of emulsion droplets for droplet digital PCR", Electrophoresis, Vol. 38, No. 2,  pp. 296-304, (2017).

[276] Y. Murata, Y. Nakashoji, M. Kondo, Y. Tanaka, M. Hashimoto, "Rapid automatic creation of monodisperse emulsion droplets by microfluidic device with degassed PDMS slab as a detachable suction actuator", Electrophoresis, Vol. 39, No. 3, pp. 504-511, (2017).

[277] B. Zhao, X. Cui, W. Ren, F. Xu, M. Liu, Z.G. Ye, "A controllable and integrated pump-enabled microfluidic chip and its application in droplets generating", Sci. Rep., Vol. 7, No. 11319, (2017).

[278] H. Mirzajani, C. Cheng, J. Wu, C.S. Ivanoff, E.N. Aghdam, H.B. Ghavifekr, "Design and characterization of a passive, disposable wirelessAC-electroosmotic lab-on-a-film for particle and fluid manipulation", Sens. Actuators B: Chem., Vol. 235, pp. 330-342, (2016).

[279] D. Agustini, M.F. Bergamini, L.H. Marcolino-Junior, "Characterization and optimization of low cost microfluidic thread based electroanalytical device for micro flow injection analysis", Anal. Chim. Acta, Vol. 951, pp. 108-115, (2017).

[280] T. Akyazi, N. Gil-Gonzálezc, L. Basabe-Desmonts, E. Castaño, M.C. Morant-Miñana, F. Benito-Lopez, "Manipulation of fluid flow direction in microfluidic paper-based analytical devices with an ionogel negative passive pump", Sens. Actuators B: Chem., Vol. 247, pp. 114-123, (2017).

[281] L. Xia, D. Dutta, "High efficiency hydrodynamic chromatography in micro- and sub-micrometer deep channels using an on-chip pressure-generation unit", Anal. Chim. Acta, Vol. 950, pp. 192-198, (2017).

[282] I. Uguz, C.M. Proctor, V.F. Curto, A.M. Pappa, M.J. Donahue, M. Ferro, R.M. Owens, D. Khodagholy, S. Inal, G.G. Malliaras, "A microfluidic ion pump for in vivo drug delivery", Adv. Mater., Vol. 29, No. 27, (2017).

[283] X. Weng, H. Jiang, D. Li, "Microfluidic DNA hybridization assays". Microfluid. Nanofluidics, Vol. 11, No. 4, pp. 367–83,( 2011) .

[284]  M.R. Saidur, A.R.A. Aziz, W.J. Basirun, "Recent advances in DNA-based electrochem- ical biosensors for heavy metal ion detection: a review". Biosens. Bioelectron., Vol. 90, pp.125–139, (2016) .

[285] S. Huang, C. Li, B. Lin, J. Qin. "Microvalve and micropump controlled shuttle flow microfluidic device for rapid DNA hybridization". Lab Chip, Vol.10, No. 21, pp. 2925–2931, (2010) .

[286] B.T. Chia, H.H. Liao, Y.J. Yang, "A novel thermo-pneumatic peristaltic microp- ump with low temperature elevation on working fluid". Sens. Actuators A Phys., Vol. 165, No. 1, pp. 86–93, (2011) .

[287] K. Ullakko, L. Wendell, A. Smith, P. Müllner, G. Hampikian, "A magnetic shape mem-ory micropump: contact-free, and compatible with PCR and human DNA profiling", Smart Mater Struct., Vol 21, No. 11, (2012).

[288] B.D. Iverson, S.V. Garimella, "Recent advances in microscale pumping technologies: a review and evaluation". Microfluid. Nanofluidics; Vol.5, No. 2, pp.145–74, (2008).

 

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